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Aspirin enhances the osteogenic and anti-inflammatory effects of human mesenchymal stem cells on osteogenic BFP-1 peptide-decorated substrates

HoggN.Darley-UsmarV.WilsonM.MoncadaS.1992Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide.Biochemical Journal.2814194240264-6021 32

At the time, only two existed: exenatide (developed by Amylin Pharmaceuticals in collaboration with Eli Lilly) and liraglutide (developed by Novo Nordisk), so they began by applying learnings from the liraglutide project

The dual-therapy group achieved 18.3% mean body weight reduction versus 14.1% in the semaglutide-only groupa 4.2 percentage point difference that reached statistical significance